Neurotrophic, Gene Regulation, and Cognitive Functions of Carboxypeptidase E-Neurotrophic Factor-α1 and Its Variants

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Pattern of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampus of Diabetic Rats

Objective(s) The aim of this study was to evaluate the effects of regular exercise in preventing diabetes complication in the hippocampus of streptozotocin (STZ)-induced diabetic rat. Materials and Methods A total of 48 male wistar rats were divided into four groups (control, control exercise, diabetic and diabetic exercise). Diabetes was induced by injection of single dose of STZ. Exercise ...

متن کامل

Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor.

Extracellular application of brain-derived neurotrophic factor (BDNF) and ciliary neurotrophic factor (CNTF) to developing neuromuscular junctions in Xenopus nerve-muscle cultures resulted in an increase in the frequency of spontaneous synaptic currents (SSCs) and in the amplitude of nerve-evoked synaptic currents. Analyses of the amplitude and time course of the SSCs suggest that these effects...

متن کامل

Action of brain-derived neurotrophic factor on function and morphology of visual cortical neurons

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

متن کامل

Action of brain-derived neurotrophic factor on function and morphology of visual cortical neurons

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

متن کامل

P36: Role of Brain-Derived Neurotrophic Factor in Pathogenesis and Treatment of Post-Traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a syndrome causing from a severe traumatic happening that leads to threatened death or injury. PTSD is associated with changes in limbic, hippocampal, and prefrontal cortical region function due to changes in synaptogenesis, dendritic modifying, and neurogenesis. Changes in neuron in PTSD patients result from pathophysiological disturbances in inflammato...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Frontiers in Neuroscience

سال: 2019

ISSN: 1662-453X

DOI: 10.3389/fnins.2019.00243